Explore individual feature distributions

Enter your feature of interest and select the cohorts to be compared against each other. Click here for a list of all the features available for comparison and their synonyms.

Assessment frequency of variables across cohorts

The plots below describe how often a specific variable was encountered in the investigated cohort datasets. Zoom into the plot to explore it in detail and see all variables on the y-axis.


CLINICAL 34 Variables
DEMOGRAPHICS 17 Variables
APOE 3 Variables
COMORBIDITIES 17 Variables
LIFESTYLE 5 Variables
FAMILY 7 Variables
CSF 14 Variables
PLASMA 8 Variables
MRI 1050 Variables
PET 23 Variables

Summary Statistics of Demographic Variables and Selected Biomarkers

The table below summarizes the demographic characteristics of each cohort and describes the distributions of some important Alzheimer’s disease biomarkers at each study's baseline. Distributions of demographic and biomarker values are described using the 25, 50 and 75% quantiles of the absolute measured values. To make biomarker measures more comparable across cohorts, we additionally report the deviation from the healthy control group of one respective cohort and a selected participant subgroup of the same study (i.e. all, healthy, MCI and AD). This deviation is given as the quantiles received when evaluating the absolute quantiles under the empirical cumulative distribution function (ECDF) of the control group of the respective cohort.


Legend


Female % Age Education APOE4 % MMSE CDR CDRSB Hippocampus A-beta tTau pTau
A4 57.7 68, 71, 75 14, 16, 18 34.3 28, 29, 30 0.0, 0.0, 0.0 0.0, 0.0, 0.0 6, 7, 7 (25, 50, 75)
ABVIB 42.9 73, 77, 82 14, 16, 18
ADNI 47.0 68, 73, 78 14, 16, 18 45.6 26, 28, 29 0.0, 0.5, 0.5 0.0, 1.0, 2.0 5948, 6864, 7651 (7, 26, 60) 596, 854, 1396 (12, 27, 57) 193, 258, 350 (36, 66, 88) 17, 24, 34 (37, 69, 91)
AIBL 57.9 67, 73, 79 10, 12, 15 36 26, 28, 30 0.0, 0.0, 0.5 0.0, 0.0, 1.0 3, 3, 3 (11, 37, 71) 445, 567, 802 (nan) 238, 366, 516 (nan) 43, 64, 81 (nan)
ANM 59.3 71, 77, 81 8, 11, 14 38.8 24, 28, 29 0.0, 0.5, 0.5 0.0, 0.5, 4.0 5311, 6270, 7142 (2, 20, 54)
ARWIBO 60.8 48, 64, 74 5, 8, 13 29.3 24, 28, 29 0.0, 0.0, 0.5 6242, 7415, 8266 (5, 30, 63) 331, 445, 667 (0, 0, 100) 232, 367, 602 (0, 0, 100) 45, 65, 93 (0, 0, 0)
DOD-ADNI 0.9 66, 68, 72 13, 15, 17 26.6 27, 29, 30 0.0, 0.0, 0.5 0.0, 0.0, 0.5 7145, 7777, 8498 (24, 50, 75) 797, 1225, 1512 (27, 51, 78) 154, 198, 254 (26, 52, 78) 13, 17, 22 (26, 53, 78)
EDSD 52.1 67, 71, 76 10, 12, 14 47 24, 27, 29 5937, 6833, 7807 (2, 17, 55) 414, 534, 852 (nan) 241, 386, 609 (nan) 51, 72, 102 (nan)
EMIF 45.9 62, 68, 74 9, 12, 15 25, 28, 29 0.5, 0.5, 0.5 6338, 7201, 7981 (5, 26, 63) 383, 522, 732 (10, 37, 66) 160, 280, 506 (37, 74, 95) 37, 52, 74 (39, 71, 93)
EPAD 56.1 60, 66, 71 12, 15, 17 39.4 28, 29, 30 0.0, 0.0, 0.5 0.0, 0.0, 0.5 4375, 4781, 5169 (25, 50, 75) 858, 1273, 1700 (25, 50, 100) 163, 202, 263 (25, 50, 75) 13, 17, 23 (25, 50, 75)
I-ADNI 58.4 65, 73, 77 5, 7, 13 18, 22, 26 0.5, 1.0, 1.0 4997, 5841, 6866
JADNI 52.7 66, 72, 77 12, 12, 16 46.1 24, 26, 29 0.0, 0.5, 0.5 0.0, 1.5, 3.0 5262, 6134, 7126 (1, 7, 40) 254, 315, 454 (7, 13, 46) 67, 101, 138 (59, 89, 96) 36, 48, 73 (59, 89, 96)
NACC 57.2 65, 72, 79 12, 16, 18 40.6 23, 27, 29 0.0, 0.5, 0.5 0.0, 1.0, 4.0 6, 6, 7 (12, 37, 67) 197, 327, 554 (9, 30, 61) 54, 115, 351 (33, 49, 78) 28, 38, 58 (26, 61, 88)
OASIS 60.8 30, 69, 78 3, 5, 12 26, 29, 30 0.0, 0.0, 0.5 5899, 6944, 7843 (11, 34, 65)
PREVENT-AD 71.0 60, 62, 67 13, 15, 18 38.5 1029, 1210, 1353 (26, 50, 75) 186, 260, 335 (26, 50, 75) 36, 46, 58 (26, 50, 75)
PharmaCog 57.1 64, 70, 74 7, 10, 13 46.2 25, 26, 28 0.5, 0.5, 0.5 5459, 6695, 7779 465, 624, 900 253, 377, 595 44, 59, 77
ROSMAP 72.8 73, 79, 84 14, 16, 18 25.1 27, 29, 30
VASCULAR 60.4 59, 64, 70 14, 16, 18 0.0, 0.0, 0.5 6758, 7399, 7949 (17, 41, 72)
VITA 59.2 75, 76, 76 9, 11, 11 20.9 27, 28, 29 0.0, 0.0, 0.0 6189, 6577, 7061 (27, 46, 78)
WMH-AD 57.8 69, 75, 80 8, 8, 8 44.9 14, 22, 25 0.5, 0.5, 1.0 4859, 5784, 6874 (0, 11, 32)